。 According to a new global epidemiological analysis, these carcinogenic infections account for about 12 percent of all newly diagnosed diseases.。 The study evaluated twelve oncogenic pathogens, including viruses, bacteria, and parasites, and found that infection control plays an important role in reducing the global burden of cancer.。
。 Helicobacter pylori causes burden of cancer, causing an estimated 760,000 cases by 2024。 Human papillomavirus has been followed closely, accounting for approximately 750,000 cases。 Hepatitis B virus has caused about 360,000 malignancies, while hepatitis C virus has been linked to about 160,000 cases.。 Epstein-Barr virus has emerged as the fourth leading cause of malignancy worldwide, causing approximately 260,000 cases, surpassing hepatitis C virus.。 This placement reflects the accumulating evidence that the Epstein-Barr virus causes not only nasal cancers and lymphomas, but also some stomach cancers.。 The analysis also evaluated human immunodeficiency virus, Merkel cell polyomavirus, Kaposi’s sarcoma herpesvirus, T-cell lymphotropic virus type 1, Schistosoma haematobium, Opisthorchis viverrini and Clonorchis sinensis.。
。 East Asia accounts for 42 percent of all infection-related cancer cases worldwide, mainly caused by Helicobacter pylori and hepatitis B virus.。 The burden of disease was also high in sub-Saharan Africa, where human papillomavirus and Kaposi’s sarcoma herpesvirus predominated, and it was coinfected with human immunodeficiency virus.。 More than three-quarters of infection-related cancers occur in low- and middle-income countries, where clinical access to prevention and treatment remains unequal.。 Most of these diseases are preventable through established interventions, including vaccination against human papillomavirus and hepatitis B virus, screening programs, targeted antimicrobial therapy for Helicobacter pylori, and treatment of viral hepatitis.。 Addressing persistent health system barriers and investing in new Epstein-Barr virus vaccines will be critical to reducing cancer incidence in the future.。
关联
鲁姆盖 H 等。 The global burden of cancer attributable to infections in 2024: a global analysis.柳叶刀 Oncol。 2026; doi:10.1016 / S1470-2045 (26) 00307-4。